The use of Cabergoline in bodybuilding

This substance is a fairly common dopaminomimetic, a derivative of ergot alkaloids. The agent is synthesized in the form of a white fine powder, which is readily soluble in ethanol, N, N-dimethylformamide and chloroform. The chemical compound is slightly soluble in 0.1 n solution of hydrochloric acid, n-hexane. The product is not soluble in water.

In medicine, Cabergoline-based drugs are used to treat hyperprolactinemia, and the substance is also used by athletes.

The drug is used to reduce prolactin levels and eliminate unwanted side effects from taking progestin anabolic steroids - trenbolone and nandrolone. During therapy, athletes monitor prolactin levels and continue to take the medication, depending on the test results. The substance is believed to eliminate fluid retention in tissues and accelerate the growth of lean muscle mass.

The drug is quickly absorbed. The maximum plasma concentration occurs in the interval from 0.5 to 4 hours. The drug is excreted by the kidneys. The half-life is 63-68 hours. Tests on rats with measurement of total radioactivity revealed that an increase in the concentration of cabergoline and its metabolites in the pituitary gland increases 100 times or more. This fact indicates a good tissue distribution of the drug.